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Horizontal gene transfer converts non-toxigenic Clostridium difficile strains into toxin producers
Clostridium difficile is a major nosocomial pathogen and the main causative agent of antibiotic-associated diarrhoea. The organism produces two potent toxins, A and B, which are its major virulence factors. These are chromosomally encoded on a region termed the pathogenicity locus (PaLoc), which als...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Pub. Group
2013
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3826655/ https://ncbi.nlm.nih.gov/pubmed/24131955 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms3601 |
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