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Assessing constraints on the path of regulatory sequence evolution

Structural and functional constraints are known to play a major role in restricting the path of evolution of protein activities. However, constraints acting on evolving transcriptional regulatory sequences, e.g. enhancers, are largely unknown. Recently, we elucidated how a novel expression pattern o...

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Detalhes bibliográficos
Main Authors: Glassford, William J., Rebeiz, Mark
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3826499/
https://ncbi.nlm.nih.gov/pubmed/24218638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2013.0026
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