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Beyond the ENCODE project: using genomics and epigenomics strategies to study enhancer evolution
The complex expression patterns observed for many genes are often regulated by distal transcription enhancers. Changes in the nucleotide sequences of enhancers may therefore lead to changes in gene expression, representing a central mechanism by which organisms evolve. With the development of the ex...
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Main Authors: | , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
The Royal Society
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3826496/ https://ncbi.nlm.nih.gov/pubmed/24218635 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2013.0022 |
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