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Beyond the ENCODE project: using genomics and epigenomics strategies to study enhancer evolution

The complex expression patterns observed for many genes are often regulated by distal transcription enhancers. Changes in the nucleotide sequences of enhancers may therefore lead to changes in gene expression, representing a central mechanism by which organisms evolve. With the development of the ex...

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Detalhes bibliográficos
Main Authors: Sakabe, Noboru Jo, Nobrega, Marcelo A.
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3826496/
https://ncbi.nlm.nih.gov/pubmed/24218635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2013.0022
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