Random phage mimotopes recognized by monoclonal antibodies against the pyruvate dehydrogenase complex-E2 (PDC-E2).

Dihydrolipoamide acetyltransferase, the E2 component of the pyruvate dehydrogenase complex (PDC-E2), is the autoantigen most commonly recognized by autoantibodies in primary biliary cirrhosis (PBC). We identified a peptide mimotope(s) of PDC-E2 by screening a phage-epitope library expressing random...

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Publié dans:	Proc Natl Acad Sci U S A
Auteurs principaux:	Cha, S, Leung, P S, Van de Water, J, Tsuneyama, K, Joplin, R E, Ansari, A A, Nakanuma, Y, Schatz, P J, Cwirla, S, Fabris, L E, Neuberger, J M, Gershwin, M E, Coppel, R L
Format:	Artigo
Langue:	Inglês
Publié:	National Academy of Sciences 1996
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC38264/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8855289/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.20.10949
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