(99m)Tc-MORF oligomers specific for bacterial ribosomal RNA as potential specific infection imaging agents

PURPOSE: Radiolabeled oligomers complementary to the 16S rRNA in bacteria were investigated as bacterial infection imaging agents. METHODS AND RESULTS: Identical sequences with backbones phosphorodiamidate morpholino (MORF), peptide nucleic acid (PNA), and phosphorothioate DNA (PS-DNA) were (99m)Tc-...

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Main Authors: Chen, Ling, Wang, Yi, Cheng, Dengfeng, Liu, Xinrong, Dou, Shuping, Liu, Guozheng, Hnatowich, Donald J., Rusckowski, Mary
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2013
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3826180/
https://ncbi.nlm.nih.gov/pubmed/24054488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2013.08.034
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