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Episodes of horizontal gene-transfer and gene-fusion led to co-existence of different metal-ion specific glyoxalase I
Glyoxalase pathway plays an important role in stress adaptation and many clinical disorders. The first enzyme of this pathway, glyoxalase I (GlxI), uses methylglyoxal as a substrate and requires either Ni(II)/Co(II) or Zn(II) for activity. Here we have investigated the origin of different metal ion...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3826101/ https://ncbi.nlm.nih.gov/pubmed/24220130 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep03076 |
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