Episodes of horizontal gene-transfer and gene-fusion led to co-existence of different metal-ion specific glyoxalase I

Glyoxalase pathway plays an important role in stress adaptation and many clinical disorders. The first enzyme of this pathway, glyoxalase I (GlxI), uses methylglyoxal as a substrate and requires either Ni(II)/Co(II) or Zn(II) for activity. Here we have investigated the origin of different metal ion...

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Detalhes bibliográficos
Main Authors: Kaur, Charanpreet, Vishnoi, Anchal, Ariyadasa, Thilini Udayangani, Bhattacharya, Alok, Singla-Pareek, Sneh Lata, Sopory, Sudhir Kumar
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3826101/
https://ncbi.nlm.nih.gov/pubmed/24220130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep03076
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