Macromolecule Extravasation—Xenograft Size Matters: A Systematic Study Using Probe-Based Confocal Laser Endomicroscopy (pCLE)

PURPOSE: Profound changes of the vasculature in tumors critically impact drug delivery and therapy response. We aimed at developing a procedure to monitor morphological and functional parameters of the vasculature in subcutaneous xenograft models commonly applied for therapy testing by using probe-b...

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Detalhes bibliográficos
Main Authors: Dietrich, Antje, Stewart, James, Huether, Melanie, Helm, Mario, Schuetze, Christina, Schnittler, Hans-Joachim, Jaffray, David A., Kunz-Schughart, Leoni A.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3826054/
https://ncbi.nlm.nih.gov/pubmed/23632953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11307-013-0641-z
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