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Cellular Mechanisms Underlying the Effects of Milrinone and Cilostazol to Suppress Arrhythmogenesis Associated with Brugada Syndrome

BACKGROUND: Brugada syndrome is an inherited disease associated with vulnerability to ventricular tachycardia and sudden cardiac death in young adults. Milrinone and cilostazol, oral phosphodiesterase (PDE) type III inhibitors, have been shown to increase I(Ca) and modestly increase heart rate by el...

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Bibliografiske detaljer
Main Authors: Szél, Tamás, Koncz, István, Antzelevitch, Charles
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3825770/
https://ncbi.nlm.nih.gov/pubmed/23911896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.hrthm.2013.07.047
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