The Retinoic Acid Receptor Agonist Am80 Increases Mucosal Inflammation in an IL-6 Dependent Manner During Trichuris muris Infection

PURPOSE: Vitamin A metabolites, such as all-trans-retinoic acid (RA) that act through the nuclear receptor; retinoic acid receptor (RAR), have been shown to polarise T cells towards Th2, and to be important in resistance to helminth infections. Co-incidentally, people harbouring intestinal parasites...

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Main Authors: Hurst, Rebecca J. M., De Caul, Adam, Little, Matthew C., Kagechika, Hiroyuki, Else, Kathryn J.
格式: Artigo
語言:Inglês
出版: Springer US 2013
主題:
Original Research
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3825562/
https://ncbi.nlm.nih.gov/pubmed/24036839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10875-013-9936-8
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