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On the interpretation of subgroup analyses in randomized trials: heterogeneity versus secondary interventions

In randomized trials with subgroup analyses, the primary treatment or intervention of interest is randomized but the secondary factors defining subgroups are not. The commentary clarifies when confounding is or is not an issue in subgroup analyses. If investigators are simply interested in targeting...

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Библиографические подробности
Главные авторы: VanderWeele, Tyler J., Knol, Mirjam J.
Формат: Artigo
Язык:Inglês
Опубликовано: 2011
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3825512/
https://ncbi.nlm.nih.gov/pubmed/21576536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7326/0003-4819-154-10-201105170-00008
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