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On the interpretation of subgroup analyses in randomized trials: heterogeneity versus secondary interventions

In randomized trials with subgroup analyses, the primary treatment or intervention of interest is randomized but the secondary factors defining subgroups are not. The commentary clarifies when confounding is or is not an issue in subgroup analyses. If investigators are simply interested in targeting...

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Detalhes bibliográficos
Main Authors: VanderWeele, Tyler J., Knol, Mirjam J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3825512/
https://ncbi.nlm.nih.gov/pubmed/21576536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7326/0003-4819-154-10-201105170-00008
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