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Chemo-sensitisation of HeLa cells to Etoposide by a Benzoxazine in the absence of DNA-PK inhibition

The benzoaxines have been developed from structurally similar chromones as specific inhibitors of the PI3K family to sensitize cancer cells to the effects of chemotherapeutic agents; most have been shown to do this through specific inhibition of DNA-PK and DNA repair mechanisms. In this study we exa...

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Detalhes bibliográficos
Principais autores: Fitzgibbon, Cheree, Ihmaid, Saleh, Al-Rawi, Jasim, Meehan-Andrews, Terri, Bradley, Christopher
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3825418/
https://ncbi.nlm.nih.gov/pubmed/24057508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10637-013-0031-z
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