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Analysis of bortezomib inhibitor docked within the catalytic subunits of the Plasmodium falciparum 20S proteasome

The three-dimensional fold of Plasmodium falciparum (Pf) 20S proteasome is similar to yeast Saccharomyces cerevisiae 20S proteasome. The twenty eight subunits complex corresponding to two copies of seven distinct α and seven distinct β subunits shares >35% sequence identity with equivalent subuni...

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Bibliographic Details
Main Authors: Sridhar, Settu, Bhat, Gayathri, Guruprasad, Kunchur
Format: Artigo
Language:Inglês
Published: Springer International Publishing 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3825223/
https://ncbi.nlm.nih.gov/pubmed/24255860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2193-1801-2-566
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