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Germline BAP1 mutation predisposes to uveal melanoma, lung adenocarcinoma, meningioma, and other cancers

OBJECTIVE: To investigate the potential contribution of germline sequence alterations in the BAP1 gene in uveal melanoma (UM) patients with possible predisposition to hereditary cancer. DESIGN: A total of 53 unrelated UM patients with high risk for hereditary cancer and five additional family member...

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Bibliografske podrobnosti
Main Authors: Abdel-Rahman, Mohamed H, Pilarski, Robert, Cebulla, Colleen M, Massengill, James B, Christopher, Benjamin N, Boru, Getachew, Hovland, Peter, Davidorf, Frederick H
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3825099/
https://ncbi.nlm.nih.gov/pubmed/21941004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jmedgenet-2011-100156
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