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Polymorphisms of the WRN gene and DNA damage of peripheral lymphocytes in age-related cataract in a Han Chinese population

Werner syndrome is caused by mutations in the DNA repair Werner helicase (WRN) gene and characterized by accelerated aging including cataracts. Age-related cataract (ARC) cases (N = 504) and controls (N = 244) were recruited from a population-based study to evaluate the association of single-nucleot...

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Autors principals: Jiang, Shengqun, Hu, Nan, Zhou, Jing, Zhang, Junfang, Gao, Ruifang, Hu, Jianyan, Guan, Huaijin
Format: Artigo
Idioma:Inglês
Publicat: Springer Netherlands 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3824989/
https://ncbi.nlm.nih.gov/pubmed/23334603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-013-9512-4
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