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Role of p38MAPK and oxidative stress in copper-induced senescence

In the present work, we indicate that copper is involved in the senescence of human diploid fibroblasts and we describe mechanisms to explain it. Using different techniques, we show for the first time an accumulation of copper in cells during replicative senescence. This accumulation seems to be co-...

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Autors principals: Boilan, Emmanuelle, Winant, Virginie, Dumortier, Elise, Piret, Jean-Pascal, Bonfitto, François, Osiewacz, Heinz D., Debacq-Chainiaux, Florence, Toussaint, Olivier
Format: Artigo
Idioma:Inglês
Publicat: Springer Netherlands 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3824981/
https://ncbi.nlm.nih.gov/pubmed/23576095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-013-9521-3
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