Instability in the Central Region of Tropomyosin Modulates the Function of Its Overlapping Ends

The causal link between disparate tropomyosin (Tm) functions and the structural instability in Tm is unknown. To test the hypothesis that the structural instability in the central region of Tm modulates the function of the overlapping ends of contiguous Tm dimers, we used transgenic mice (Tm(DM)) th...

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Bibliografiske detaljer
Main Authors: Mamidi, Ranganath, Muthuchamy, Mariappan, Chandra, Murali
Format: Artigo
Sprog:Inglês
Udgivet: The Biophysical Society 2013
Fag:
Molecular Machines, Motors and Nanoscale Biophysics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3824695/
https://ncbi.nlm.nih.gov/pubmed/24209855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2013.09.026
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