Tumor suppressor PDCD4 modulates miR-184-mediated direct suppression of C-MYC and BCL2 blocking cell growth and survival in nasopharyngeal carcinoma

Programmed cell death 4 (PDCD4), a novel tumor suppressor, inhibits cell proliferation, migration and invasion as well as promotes cell apoptosis in tumors. However, the molecular mechanism of its tumor-suppressive function remains largely unknown in tumors including nasopharyngeal carcinoma (NPC)....

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Zhen, Yan, Liu, Zhen, Yang, Huiling, Yu, Xiaoli, Wu, Qiangyun, Hua, Shengni, Long, Xiaobin, Jiang, Qingping, Song, Ye, Cheng, Chao, Wang, Hao, Zhao, Menyang, Fu, Qiaofen, Lyu, Xiaoming, Chen, Yiyu, Fan, Yue, Liu, Yan, Li, Xin, Fang, Weiyi
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2013
Sujets:
Original Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3824685/
https://ncbi.nlm.nih.gov/pubmed/24157866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.376
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