Gpr97 is essential for the follicular versus marginal zone B-lymphocyte fate decision

Gpr97 is an orphan adhesion GPCR and is highly conserved among species. Up to now, its physiological function remains largely unknown. Here, we show that Gpr97 deficiency results in an extensive reduction in B220(+) lymphocytes in mice. More intensive analyses reveal an expanded marginal zone but a...

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Detalhes bibliográficos
Main Authors: Wang, J-j, Zhang, L-l, Zhang, Hong-x, Shen, C-l, Lu, S-y, Kuang, Y, Wan, Y-h, Wang, W-g, Yan, H-m, Dang, S-y, Fei, J, Jin, X-l, Wang, Z-g
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3824656/
https://ncbi.nlm.nih.gov/pubmed/24113187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.346
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