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Alteplase treatment does not increase brain injury after mechanical middle cerebral artery occlusion in the rat
Recanalization of an occluded vessel with recombinant tissue plasminogen activator is an effective strategy for treating acute ischemic stroke. Recombinant tissue plasminogen activator is administered as alteplase, a formulation containing many excipients including L-arginine, the substrate for nitr...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3824188/ https://ncbi.nlm.nih.gov/pubmed/23963368 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2013.148 |
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