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LPS-Treated Macrophage Cytokines Repress Surfactant Protein–B in Lung Epithelial Cells

In the mouse lung, Escherichia coli LPS can decrease surfactant protein–B (SFTPB) mRNA and protein concentrations. LPS also regulates the expression, synthesis, and concentrations of a variety of gene and metabolic products that inhibit SFTPB gene expression. The purpose of the present study was to...

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Bibliographic Details
Main Authors: Bein, Kiflai, Di Giuseppe, Michelangelo, Mischler, Steven E., Ortiz, Luis A., Leikauf, George D.
Format: Artigo
Language:Inglês
Published: American Thoracic Society 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3824031/
https://ncbi.nlm.nih.gov/pubmed/23590297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2012-0283OC
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