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Bromelain Decreases Neutrophil Interactions with P-Selectin, but Not E-Selectin, In Vitro by Proteolytic Cleavage of P-Selectin Glycoprotein Ligand-1

Stem bromelain, a cysteine protease isolated from pineapples, is a natural anti-inflammatory treatment, yet its mechanism of action remains unclear. Curious as to whether bromelain might affect selectin-mediated leukocyte rolling, we studied the ability of bromelain-treated human neutrophils to teth...

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Autors principals: Banks, Jessica M., Herman, Christine T., Bailey, Ryan C.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3823987/
https://ncbi.nlm.nih.gov/pubmed/24244398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0078988
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