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Disappearance of Hypoxic Pulmonary Vasoconstriction and O(2)-Sensitive Nonselective Cationic Current in Arterial Myocytes of Rats Under Ambient Hypoxia

Acute hypoxia induces contraction of pulmonary artery (PA) to protect ventilation/perfusion mismatch in lungs. As for the cellular mechanism of hypoxic pulmonary vasoconstriction (HPV), hypoxic inhibition of voltage-gated K(+) channel (Kv) in PA smooth muscle cell (PASMC) has been suggested. In addi...

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Detalhes bibliográficos
Main Authors: Yoo, Hae Young, Kim, Sung Joon
Formato: Artigo
Idioma:Inglês
Publicado em: The Korean Physiological Society and The Korean Society of Pharmacology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3823961/
https://ncbi.nlm.nih.gov/pubmed/24227949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4196/kjpp.2013.17.5.463
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