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Poly-LacNAc as an Age-Specific Ligand for Rotavirus P[11] in Neonates and Infants

Rotavirus (RV) P[11] is an unique genotype that infects neonates. The mechanism of such age-specific host restriction remains unknown. In this study, we explored host mucosal glycans as a potential age-specific factor for attachment of P[11] RVs. Using in vitro binding assays, we demonstrated that V...

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Detalhes bibliográficos
Main Authors: Liu, Yang, Huang, Pengwei, Jiang, Baoming, Tan, Ming, Morrow, Ardythe L., Jiang, Xi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3823915/
https://ncbi.nlm.nih.gov/pubmed/24244290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0078113
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