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MicroRNA-142 Reduces Monoamine Oxidase A Expression and Activity in Neuronal Cells by Downregulating SIRT1

Aberrant expression of microRNAs (miRs) has been implicated in the pathogenesis of several neurodegenerative disorders. In HIV-associated neurocognitive disorders (HAND), miR-142 was found to be upregulated in neurons and myeloid cells in the brain. We investigated the downstream effects of chronic...

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Bibliographische Detailangaben
Hauptverfasser: Datta Chaudhuri, Amrita, Yelamanchili, Sowmya V., Fox, Howard S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3823651/
https://ncbi.nlm.nih.gov/pubmed/24244526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0079579
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