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The Cortical Actin Determines Different Susceptibility of Naïve and Memory CD4+ T Cells to HIV-1 Cell-to-Cell Transmission and Infection

Memory CD4+ T cells are preferentially infected by HIV-1 compared to naïve cells. HIV-1 fusion and entry is a dynamic process in which the cytoskeleton plays an important role by allowing virion internalization and uncoating. Here, we evaluate the role of the cortical actin in cell-to-cell transfer...

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Autors principals: Permanyer, Marc, Pauls, Eduardo, Badia, Roger, Esté, José A., Ballana, Ester
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3823590/
https://ncbi.nlm.nih.gov/pubmed/24244453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0079221
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