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Detection of Single Enzymatic Events in Rare- or Single Cells Using Microfluidics

In the present study we demonstrate highly sensitive detection of rare, aberrant cells in a population of wild-type human cells by combining a rolling circle-enhanced enzyme activity single molecule detection assay with a custom designed microfluidic device. Besides reliable detection of low concent...

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Bibliografski detalji
Glavni autori: Juul, Sissel, Ho, Yi-Ping, Koch, Jørn, Andersen, Felicie F., Stougaard, Magnus, Leong, Kam W., Knudsen, Birgitta R.
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3823540/
https://ncbi.nlm.nih.gov/pubmed/21936557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/nn203012q
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