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Detection of Single Enzymatic Events in Rare- or Single Cells Using Microfluidics
In the present study we demonstrate highly sensitive detection of rare, aberrant cells in a population of wild-type human cells by combining a rolling circle-enhanced enzyme activity single molecule detection assay with a custom designed microfluidic device. Besides reliable detection of low concent...
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| Autores principales: | , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2011
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3823540/ https://ncbi.nlm.nih.gov/pubmed/21936557 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/nn203012q |
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