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Modulation of Hydrogel Nanoparticle Intracellular Trafficking by Multivalent Surface Engineering with Tumor Targeting Peptide()

Surface engineering of a hydrogel nanoparticle (NP) with the tumor-targeting ligand, F3 peptide, enhances both the NP’s binding affinity for, and internalization by, nucleolin overexpressing tumor cells. Remarkably, the F3-functionalized NPs consistently exhibited significantly lower trafficking to...

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Bibliographische Detailangaben
Hauptverfasser: Karamchand, Leshern, Kim, Gwangseong, Wang, Shouyan, Hah, Hoe Jin, Ray, Aniruddha, Jiddou, Ruba, Lee, Yong-Eun Koo, Philbert, Martin A., Kopelman, Raoul
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3823366/
https://ncbi.nlm.nih.gov/pubmed/24056573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c3nr00908d
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