Interplay between Ca(2+) cycling and mitochondrial permeability transition pores promotes reperfusion-induced injury of cardiac myocytes

Uncontrolled release of Ca(2+) from the sarcoplasmic reticulum (SR) contributes to the reperfusion-induced cardiomyocyte injury, e.g. hypercontracture and necrosis. To find out the underlying cellular mechanisms of this phenomenon, we investigated whether the opening of mitochondrial permeability tr...

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Bibliographic Details
Main Authors: Abdallah, Yaser, Kasseckert, Sascha A, Iraqi, Wisam, Said, Maher, Shahzad, Tayyab, Erdogan, Ali, Neuhof, Christiane, Gündüz, Dürsün, Schlüter, Klaus-Dieter, Tillmanns, Harald, Piper, H Michael, Reusch, H Peter, Ladilov, Yury
Format: Artigo
Language:Inglês
Published: Blackwell Publishing Ltd 2011
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3822958/
https://ncbi.nlm.nih.gov/pubmed/21199327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2010.01249.x
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