Exendin-4 regulates pancreatic ABCA1 transcription via CaMKK/CaMKIV pathway

ATP-binding cassette transporter A1 (ABCA1) in pancreatic β cells influences insulin secretion and glucose homeostasis. This study investigates whether the long-acting agonist of the glucagon-like peptide 1, namely exendin-4, which mediates stimulatory effects on ABCA1 gene expression, could interfe...

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Hlavní autoři: Li, Junhua, Murao, Koji, Imachi, Hitomi, Masugata, Hisashi, Iwama, Hisakazu, Tada, Satoshi, Zhang, Guo-Xing, Kobayashi, Ryoji, Ishida, Toshihiko, Tokumitsu, Hiroshi
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Publishing Ltd 2010
Témata:
BRIEF/SHORT Communication
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3822745/
https://ncbi.nlm.nih.gov/pubmed/19874424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2009.00955.x
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