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The Akt1 isoform is an essential mediator of ischaemic preconditioning

Phosphatidyl-inositol-3-kinase (PI3K)-Akt pathway is essential for conferring cardioprotection in response to ischaemic preconditioning (IPC) stimulus. However, the role of the individual Akt isoforms expressed in the heart in mediating the protective response to IPC is unknown. In this study, we in...

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Detalhes bibliográficos
Main Authors: Kunuthur, Suma P, Mocanu, Mihaela M, Hemmings, Brian A, Hausenloy, Derek J, Yellon, Derek M
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3822687/
https://ncbi.nlm.nih.gov/pubmed/22117619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2011.01491.x
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