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HDAC4/5-HMGB1 signalling mediated by NADPH oxidase activity contributes to cerebral ischaemia/reperfusion injury

Histone deacetylases (HDACs)-mediated epigenetic mechanisms play critical roles in the homeostasis of histone acetylation and gene transcription. HDAC inhibitors have displayed neuroprotective properties in animal models for various neurological diseases including Alzheimer's disease and ischae...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: He, Min, Zhang, Bin, Wei, Xinbing, Wang, Ziying, Fan, Baoxia, Du, Pengchao, Zhang, Yan, Jian, Wencheng, Chen, Lin, Wang, Linlin, Fang, Hao, Li, Xiang, Wang, Ping-An, Yi, Fan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Publishing Ltd 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3822653/
https://ncbi.nlm.nih.gov/pubmed/23480850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12040
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