Immunosuppression induced by immature dendritic cells is mediated by TGF-β/IL-10 double-positive CD4(+) regulatory T cells

Dendritic cells (DC) have important functions in T cell immunity and T cell tolerance. Previously, it was believed that T cell unresponsiveness induced by immature DC (iDC) is caused by the absence of inflammatory signals in steady-state in vivo conditions and by the low expression levels of costimu...

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Detalhes bibliográficos
Main Authors: Cools, N, Van Tendeloo, VFI, Smits, ELJM, Lenjou, M, Nijs, G, Van Bockstaele, DR, Berneman, ZN, Ponsaerts, P
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2008
Assuntos:
Images in Cellular / Molecular Medicine
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3822554/
https://ncbi.nlm.nih.gov/pubmed/18419605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2007.00084.x
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