Moderate increase in histone acetylation activates the mouse mammary tumor virus promoter and remodels its nucleosome structure.
The mouse mammary tumor virus (MMTV) promoter is regulated by steroid hormones through a hormone-responsive region that is organized in a positioned nucleosome. Hormone induction leads to a structural change of this nucleosome which makes its DNA more sensitive to cleavage by DNase I and enables sim...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1996
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC38225/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8855250/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.20.10741 |
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