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Expression of the BMP Receptor Alk3 in the Second Heart Field is Essential for Development of the Dorsal Mesenchymal Protrusion and Atrioventricular Septation

RATIONALE: The Dorsal Mesenchymal Protrusion (DMP) is a prong of mesenchyme derived from the Second Heart Field (SHF) located at the venous pole of the developing heart. Recent studies have shown that perturbation of its development is associated with the pathogenesis of atrioventricular septal defe...

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Autores principales: Briggs, Laura E., Phelps, Aimee L., Brown, Elizabeth, Kakarla, Jayant, Anderson, Robert H., van den Hoff, Maurice J. B., Wessels, Andy
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3822333/
https://ncbi.nlm.nih.gov/pubmed/23584254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.112.300821
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