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A Mathematical Model of the Enhancement of Tumor Vaccine Efficacy by Immunotherapy

TGF-β is an immunoregulatory protein that contributes to inadequate antitumor immune responses in cancer patients. Recent experimental data suggests that TGF-β inhibition alone, provides few clinical benefits, yet it can significantly amplify the anti-tumor immune response when combined with a tumor...

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Detalhes bibliográficos
Main Authors: Wilson, Shelby, Levy, Doron
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3822329/
https://ncbi.nlm.nih.gov/pubmed/22438084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11538-012-9722-4
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