Bioluminescence Imaging in Mouse Models Quantifies β Cell Mass in the Pancreas and After Islet Transplantation

PURPOSE: We developed a mouse model that enables non-invasive assessment of changes in β cell mass. PROCEDURES: We generated a transgenic mouse expressing luciferase under control of the mouse insulin I promoter [mouse insulin promoter-luciferase-Vanderbilt University (MIP-Luc-VU)] and characterized...

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Hauptverfasser: Virostko, John, Radhika, Aramandla, Poffenberger, Greg, Chen, Zhongyi, Brissova, Marcela, Gilchrist, Joshua, Coleman, Brian, Gannon, Maureen, Jansen, E. Duco, Powers, Alvin C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3822006/
https://ncbi.nlm.nih.gov/pubmed/19548035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11307-009-0240-1
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