Endothelial FoxO1 is an intrinsic regulator of thrombospondin 1 expression that restrains angiogenesis in ischemic muscle

Peripheral artery disease (PAD) is characterized by chronic muscle ischemia. Compensatory angiogenesis is minimal within ischemic muscle despite an increase in angiogenic factors. This may occur due to the prevalence of angiostatic factors. Regulatory mechanisms that could evoke an angiostatic envir...

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Main Authors: Roudier, Emilie, Milkiewicz, Malgorzata, Birot, Olivier, Slopack, Dara, Montelius, Andreas, Gustafsson, Thomas, Paik, Ji Hye, DePinho, Ronald A., Casale, George P., Pipinos, Iraklis I., Haas, Tara L.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2013
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3822003/
https://ncbi.nlm.nih.gov/pubmed/23677673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10456-013-9353-x
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