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Purification of telomerase from Euplotes aediculatus: requirement of a primer 3' overhang.

Telomerase is a ribonucleoprotein enzyme that uses its internal RNA moiety as a template for synthesis of telomeric repeats at chromosome ends. Here we report the purification of telomerase from Euplotes aediculatus by affinity chromatography with antisense 2'-O-methyl oligonucleotides, a method tha...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Lingner, J, Cech, T R
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1996
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Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC38220/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8855245/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.20.10712
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