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MECHANISM OF INHIBITION OF TUBULOGLOMERULAR FEEDBACK (TGF) BY CARBON MONOXIDE AND cGMP

Tubuloglomerular feedback (TGF) is a mechanism that senses NaCl in the macula densa (MD) and causes constriction of the afferent arteriole (Af-Art). Carbon monoxide (CO), either endogenous or exogenous, inhibits TGF at least in part via cGMP. We hypothesize that CO in the MD, acting via both cGMP-de...

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Autors principals: Ren, YiLin, D’Ambrosio, Martin A., Garvin, Jeffrey L., Wang, Hong, Carretero, Oscar A.
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3821182/
https://ncbi.nlm.nih.gov/pubmed/23648700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.113.01164
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