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Deep Coverage of the Escherichia coli Proteome Enables the Assessment of False Discovery Rates in Simple Proteogenomic Experiments
Recent advances in mass spectrometry (MS) have led to increased applications of shotgun proteomics to the refinement of genome annotation. The typical “proteo-genomic” workflows rely on the mapping of peptide MS/MS spectra onto databases derived via six-frame translation of the genome sequence. Thes...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The American Society for Biochemistry and Molecular Biology
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3820952/ https://ncbi.nlm.nih.gov/pubmed/23908556 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M113.029165 |
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