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Development of a 5-plex SILAC Method Tuned for the Quantitation of Tyrosine Phosphorylation Dynamics

The propagation of phosphorylation downstream of receptor tyrosine kinases is a key dynamic cellular event involved in signal transduction, which is often deregulated in disease states such as cancer. Probing phosphorylation dynamics is therefore crucial for understanding receptor tyrosine kinases&#...

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Hlavní autoři: Tzouros, Manuel, Golling, Sabrina, Avila, David, Lamerz, Jens, Berrera, Marco, Ebeling, Martin, Langen, Hanno, Augustin, Angélique
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Biochemistry and Molecular Biology 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3820944/
https://ncbi.nlm.nih.gov/pubmed/23882028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.O113.027342
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