Selective Targeting of the Cysteine Proteome by Thioredoxin and Glutathione Redox Systems

Thioredoxin (Trx) and GSH are the major thiol antioxidants protecting cells from oxidative stress-induced cytotoxicity. Redox states of Trx and GSH have been used as indicators of oxidative stress. Accumulating studies suggest that Trx and GSH redox systems regulate cell signaling and metabolic path...

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Detalhes bibliográficos
Main Authors: Go, Young-Mi, Roede, James R., Walker, Douglas I., Duong, Duc M., Seyfried, Nicholas T., Orr, Michael, Liang, Yongliang, Pennell, Kurt D., Jones, Dean P.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3820939/
https://ncbi.nlm.nih.gov/pubmed/23946468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M113.030437
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