Pituitary Adenylate Cyclase-activating Polypeptide Type 1 Receptor (PAC1) Gene Is Suppressed by Transglutaminase 2 Activation

Pituitary adenylate cyclase-activating polypeptide (PACAP) functions as a neuroprotective factor through the PACAP type 1 receptor, PAC1. In a previous work, we demonstrated that nerve growth factor augmented PAC1 gene expression through the activation of Sp1 via the Ras/MAPK pathway. We also observ...

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Autori principali: Miura, Ayako, Kambe, Yuki, Inoue, Kazuhiko, Tatsukawa, Hideki, Kurihara, Takashi, Griffin, Martin, Kojima, Soichi, Miyata, Atsuro
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2013
Soggetti:
Neurobiology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3820906/
https://ncbi.nlm.nih.gov/pubmed/24045949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.452706
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