Serum- and Glucocorticoid-induced Protein Kinase 1 (SGK1) Is Regulated by Store-operated Ca(2+) Entry and Mediates Cytoprotection against Necrotic Cell Death

Serum and glucocorticoid-regulated kinase 1 (SGK1) encodes a phosphatidylinositol 3-kinase-dependent serine/threonine kinase that is rapidly induced in response to cellular stressors and is an important cell survival signal. Previous studies have suggested that an increase in cytoplasmic Ca(2+) conc...

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Główni autorzy: Brickley, Deanna R., Agyeman, Abena S., Kopp, Richard F., Hall, Ben A., Harbeck, Mark C., Belova, Larissa, Volden, Paul A., Wu, Wei, Roe, Michael W., Conzen, Suzanne D.
Format: Artigo
Język:Inglês
Wydane: American Society for Biochemistry and Molecular Biology 2013
Hasła przedmiotowe:
Signal Transduction
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3820905/
https://ncbi.nlm.nih.gov/pubmed/24043625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.507210
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