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Inhibition of Snail1-DNA-PKcs Protein-Protein Interface Sensitizes Cancer Cells and Inhibits Tumor Metastasis

Our previous study suggested that the DNA-dependent protein kinase catalytic subunit (DNA-PKcs) interacts with Snail1, which affects genomic instability, sensitivity to DNA-damaging agents, and migration of tumor cells by reciprocal regulation between DNA-PKcs and Snail1. Here, we further investigat...

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Detalhes bibliográficos
Main Authors: Kang, Ga-Young, Pyun, Bo-Jeong, Seo, Haeng Ran, Jin, Yeung Bae, Lee, Hae-June, Lee, Yoon-Jin, Lee, Yun-Sil
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3820884/
https://ncbi.nlm.nih.gov/pubmed/24085291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.479840
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