Artificial Sweeteners Stimulate Adipogenesis and Suppress Lipolysis Independently of Sweet Taste Receptors

G protein-coupled receptors mediate responses to a myriad of ligands, some of which regulate adipocyte differentiation and metabolism. The sweet taste receptors T1R2 and T1R3 are G protein-coupled receptors that function as carbohydrate sensors in taste buds, gut, and pancreas. Here we report that s...

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Autori principali: Simon, Becky R., Parlee, Sebastian D., Learman, Brian S., Mori, Hiroyuki, Scheller, Erica L., Cawthorn, William P., Ning, Xiaomin, Gallagher, Katherine, Tyrberg, Björn, Assadi-Porter, Fariba M., Evans, Charles R., MacDougald, Ormond A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2013
Soggetti:
Metabolism
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3820882/
https://ncbi.nlm.nih.gov/pubmed/24068707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.514034
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