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Molecular Basis of Cannabinoid CB1 Receptor Coupling to the G Protein Heterotrimer Gα(i)βγ: IDENTIFICATION OF KEY CB1 CONTACTS WITH THE C-TERMINAL HELIX α(5) OF Gα(i)
The cannabinoid (CB1) receptor is a member of the rhodopsin-like G protein-coupled receptor superfamily. The human CB1 receptor, which is among the most expressed receptors in the brain, has been implicated in several disease states, including drug addiction, anxiety, depression, obesity, and chroni...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3820880/ https://ncbi.nlm.nih.gov/pubmed/24092756 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.489153 |
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