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A Role for Host Activation-Induced Cytidine Deaminase in Innate Immune Defense against KSHV
Activation-induced cytidine deaminase (AID) is specifically induced in germinal center B cells to carry out somatic hypermutation and class-switch recombination, two processes responsible for antibody diversification. Because of its mutagenic potential, AID expression and activity are tightly regula...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3820765/ https://ncbi.nlm.nih.gov/pubmed/24244169 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003748 |
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