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Rabies Virus Vector Transgene Expression Level and Cytotoxicity Improvement Induced by Deletion of Glycoprotein Gene

The glycoprotein (G) of rabies virus (RV) is required for binding to neuronal receptors and for viral entry. G-deleted RV vector is a powerful tool for investigating the organization and function of the neural circuits. It gives the investigator the ability to genetically target initial infection to...

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Detalhes bibliográficos
Main Authors: Ohara, Shinya, Sato, Sho, Oyama, Kei, Tsutsui, Ken-Ichiro, Iijima, Toshio
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3820615/
https://ncbi.nlm.nih.gov/pubmed/24244660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0080245
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